eISSN 2373-3551


WELCOME TO Medical Science Hypotheses

A new journal in the Medical Science Monitor family has just opened.
Medical Science Hypotheses has developed as an independent title in 2014 out of the highly popular Hypothesis section of the Medical Science Monitor. The Editors believe that hypothesis reports are inspiring source of information in developing new research areas or therapies. In addition to the inspiration, these reports are an important basis for further and more advanced research on diagnosis, treatment development, causes and outcomes of disease.
The aim of the Journal is to gather hypothesis reports across all medical disciplines, thereby integrating international medical knowledge.

As a continuation of the Medical Science Monitor, the new journal will be added to PubMed Central / PubMed and Medline after a short period of evaluation of the first 15 published papers. We are looking forward to your submission.

Table of Content Volume 4, 2017

Published: 2017-06-22

Amphetamine Use in Stroke Recovery: Rehabilitative Training Combined with Brain Stimulation

Shahid Bashir, Kaleem Imdad, Isaac Túnez

(Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia)

Med Sci Hypotheses 2017; 4:29-33

DOI: 10.12659/MSH.903804

ABSTRACT: Stroke is a physiological disorder that occurs when a prolonged local interruption of cerebral blood flow leads to massive neuronal death and short- or long-term functional impairment. People who experience major stroke retain some of their neural functional abilities for weeks and months, as abundantly reported earlier, and this recovery can reach a plateau at 6 months or later after injury. The focal goal of any stroke therapy in humans is the rehabilitation of functional capabilities related to autonomy and quality of life. In recent times, blending of acute d-Amph administration with rehabilitative training (RT) has revealed enormous remedial effects in animal models of stroke in clinical studies. In the present study, we hypothesized that the synergistic therapeutic effects of d-Amph coupled with RT administered during the early or late sub-acute period, combined with magnetic field stimulation, would improve neuronal activation, anatomic plasticity, and skilled motor functions in a middle-age rodent model of stroke. The results of the present study will advance understanding of the potential mechanism of d-Amph coupled with RT and magnetic field stimulation and their converging therapeutic effects in stroke recovery.

Keywords: Heat Stroke, Magnetic Field Therapy, Rehabilitation


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